My Experience with the DUTCH Test by Precision Analytical

Hi friends! Several months ago - back in the spring - I told you guys that I was taking the DUTCH Complete test and then life got crazy and I never really mentioned it again, so in today’s episode, I’m going to give you an update on my experience with the DUTCH test, what I’ve learned from it, and how it’s benefited my health.  

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The DUTCH test is a functional hormone test made by a company called Precision Analytical, a CLIA-certified laboratory. DUTCH stands for Dried Urine Test for Comprehensive Hormones and as the name indicates, their tests evaluate various hormone levels. Some of their tests evaluate sex hormones like estrogen, progesterone, and testosterone (as well as their metabolites - more on this later), and some look at adrenal hormones like cortisol and DHEA-S, and some tests look at all of it. Their tests also evaluate oxidative stress markers as well as certain vitamin and organic acid markers. 

My Experience

I chose to go with the DUTCH complete test as it was the most comprehensive test at the time. I wanted an overall look at my sex hormones as well as my adrenal hormones. Some of you may remember that I posted a few stories on Instagram right before I sent my test back in where I showed you what all was included in the test, what it looks like, etc. (those are still in my Endo highlight if you’d like to go back and see those). As I mentioned, this is a dried urine test, so the kit includes cards for you to collect several urine samples over a 24-hour period. It also includes a health history form for all of your medical history as well as places for you to indicate any symptoms you’re experiencing or concerns that you have. Once you’ve completed all of your samples, you seal everything up and mail it back to Precision Analytical in a prepaid package envelope. It’s honestly very easy to do and the instructions are very detailed and clear. 

My full report with my results was emailed to me within two weeks of when I mailed in the test.

Who is the DUTCH test for?

In my opinion, this test can be beneficial for anyone, because I always think that more information about your body and how it’s functioning is helpful. Mainly, I think that the DUTCH test can be very helpful for anyone experiencing hormonal imbalance symptoms or a hormone-driven condition like PCOS, Endometriosis, Uterine Fibroids, infertility, etc. Also, this test can be helpful for anyone with a history of estrogen-driven cancer in their families such as breast or prostate cancer, or anyone who is concerned about their risk.

DUTCH Results Report

I’m going to walk you through some of my results so you can better understand what this test looks like and how you can use the results to support your health. I will say that this is a very in-depth report, so unless you are trained in hormone health and detox pathways, you will need the help of a physician trained in these areas - likely a functional medicine doctor. The report does provide a summary at the end of each section of the results, but for an in-depth understanding and how to address/treat any issues that are found, you will need the support of someone trained in this. I do have a few functional med Drs that I can refer you to, if you’d like to send me an email or DM, I can help you with that. 

• The first page starts with a summary of the main 3 sex hormones - Estradiol (E2), progesterone, and testosterone - and adrenal hormones - total DHEA and free Cortisol. (So for me, it showed that my overall estrogen was on the high end of normal, my progesterone was on the low end of normal, and my testosterone was right in the middle of the normal range. My cortisol pattern looked good, although the free cortisol was a little more on the low end. My total DHEA also looked good. No real surprises here for me - it’s pretty much what I expected)

• Page 2 of the report lists the hormone metabolites (the liver breaks down active hormones into water-soluble metabolites in order to be excreted from the body). There are different metabolites for each hormone and measuring these helps you to know how your body is clearing excess hormones. If your body isn’t doing this well, it can increase your risk for hormone-driven disease and cancer. For example, the hormone estrogen actually has 3 primary forms - Estrone (E1), Estradiol (E2), and Estriol (E3) and each can be broken down and pass through a few different metabolite pathways to be eventually excreted from the body. The ideal pathway is called the 2-OH pathway and it is considered the safest or most protective, meaning it’s the least likely to bind to something it shouldn’t or cause any damage to your DNA on its way out. On the other hand, there is the 4-OH pathway that is the least desired pathway because when not properly detoxified these metabolites are more likely to cause damage. When your body seems to prefer this pathway and doesn’t do a good job of detoxification, this can increase your risk of estrogen-driven cancer, specifically breast cancer. This is a big deal and something that is important to know. There are ways that you can support your body’s detoxification pathways but you need to know as soon as possible, rather than waiting until it’s becoming a problem to address it.

• Page 3 is a visual representation of each hormone and its metabolites and their pathways. It also allows you to see how your body prefers to metabolize hormones. 

• Pages 4 and 5 give you a similar structure as 3-4 but with adrenal hormones as well as a helpful diagram that shows the process of how our stress hormones are triggered and the pathways that they follow throughout the body. 

• Page 6 lists the organic acids that are tested which include markers for vitamins B12 and B6, and glutathione (a major antioxidant that is very important for detoxification) as well as metabolites for dopamine, norepinephrine/epinephrine, melatonin, and a marker for oxidative stress/DNA damage. 

• The remaining pages provide a summary of a few clinical notes that would be made on any out-of-range results that you have, as well as explanations for each marker and how to read the report. 

As you can see, this is a very in-depth report that goes into way more detail than a normal hormone panel that your PCP or GYN would order. I also love the fact that since this test is measured with urine, it can look at how your body is detoxing the hormones. This is something that a serum or blood test can’t evaluate in the same way. 

Again, I highly recommend this test for anyone who feels that there is something off with their hormones as well as anyone who knows that they have estrogen dominance issues or who may have elevated risk factors for hormone-driven disease or cancer/has a family history of breast or prostate cancers. 

You can order the test through a DUTCH-affiliated provider by searching their website or you can order the test online for yourself and have it sent to your home. DUTCH gave me a coupon code to share with you if you want to order it for yourself - use the code adhc100 for $100 off the cost of the test. 

If you have any questions about the test or need help getting in touch with a physician that could help interpret your results, feel free to send an email to info@yourhealthforward.com or send me a DM on Instagram. 

Why Liver Health Matters

Hi friends! In today’s episode, we are talking about our livers and why it’s so important that we take good care of them! The health of our livers is probably not something that often crosses our minds, but it is one of the most important organs in our bodies both for everyday function and long-term health. So let’s get into talking about the liver…

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The liver is the unsung hero of our bodies. It performs over 500 essential functions and unless something is going wrong, it rarely ever gets noticed. Most people I know don’t go around thinking about their livers throughout the day, yet it’s functions are vital to all other body systems’ ability to function. 

For example, here are a few of the essential functions the liver is responsible for:

Digestion and absorption

Our livers help turn our food into energy. It stores and distributes both fat and glucose, as well as metabolizes both cholesterol and protein.  It produces bile which is vital for digestion and absorption of key vitamins and nutrients and then distributes those nutrients out to the body. It also produces key enzymes that are needed for other chemical reactions all over the body. In addition to distribution, it also stores vitamins and minerals that will be needed in the future. So just by listing these few things, this shows that our livers help regulate our blood sugar, cholesterol, and hormone levels. 

Immune Function

Our livers produce of certain proteins and components of the immune system such as cytokines as well as various other immune cells. Our livers maintain a certain amount of controlled inflammation which assists the body in detoxification, but when this becomes uncontrolled or dysregulated, it can lead to systemic inflammation which damages the immune system and can even lead to auto-immunity or cancer. 

Hormone Function

The liver is hugely important for hormone health. Our livers create proteins and cholesterol that carry hormones all over the body. In addition, it also helps deactivate hormones and assist with ridding our bodies of excess hormones, or ones that we no longer need. This process is vitally important. For example, with the hormone estrogen, our livers actually regulate which kind of estrogens our bodies produce, as well as help with the processes that remove excess estrogen from the body. Without this essential function, an excess of estrogens can build in the body leading to estrogen-dominant diseases and cancer.  

Detox 

The function that our livers are best know for is detoxification. The liver is responsible for the movement of the blood in our bodies. As a matter of fact, almost 1½ liters of blood pass through our liver every single minute in order to be filtered. Through this process it extracts toxins and stores nutrients for later use (which we discussed when talking about digestion and absorption). The liver detoxifies in three phases that must stay in sync with each other. 

Phase One is bioidentification. This is when your body sends out enzymes that put a red flag on all toxins. Phase two is conjugation. This is when the body attaches molecules to those flagged toxins to make them either water soluble or fat soluble. Phase three is elimination. This is when the body actually flushes the toxins from our bodies when we use the bathroom (and sometimes through sweat). If one of these phases isn’t working correctly, it can damage our body’s cells and allow the toxins to continue to circulate in our bodies, further taxing our livers and creating a loop of inflammation. Every single substance we breathe, ingest, or absorb through our skin will pass through our liver, which creates a huge workload for it every single day. 

The point here is that every other system in the body is dependent on the function of the liver and when our livers are healthy, and functioning well, this works great! However, the truth is that the majority of Americans are walking around with less-than-healthy livers. 

What happens when our livers aren’t healthy

It’s estimated that up to 90 million Americans (that’s almost ⅓ of the American population) has Fatty Liver Disease, which is basically inflammation of the liver that occurs when apprx. 5% of cells in the liver are replaced with fat cells. This causes the liver to be unable to keep up with it’s 500+ essential functions and add to systemic inflammation in the rest of the body, which can lead to other chronic diseases like heart disease, diabetes, even Alzheimers and Dementia. 

If Fatty Liver Disease is left untreated, it can progress into Fibrosis, and even Cirrhosis of the liver, which leads to liver failure (fatal). Liver Disease doesn’t just occur because of alcohol or drug use or Hepatitis. Non-alcoholic fatty liver disease is the most common form of liver disease and is caused by a combination of lifestyle and genetics - most commonly high-starch/high-sugar diets, insufficient protein intake, intake of trans fats and artificial chemicals, unresolved emotions and trauma, lack of movement in the lymphatic system, and overexposure to environmental toxins. It’s not usually only too much fat, as the name would suggest.

Symptoms of an unhealthy liver or fatty liver disease

There aren’t always immediate symptoms, which can make it tricky. When symptoms do occur, some common ones are:

• Abdominal pain, fullness in the upper right side

• Nausea, loss of appetite (especially in the AM)

• Swelling in legs/abdomen

• Fatigue

• Brain Fog/confusion

• Waking up at night in the 2-3 am range regularly

You can ask your provider to run labs to check enzyme levels most commonly found in the liver ALT and AST. If either level is over 30, especially ALT, this can be indicative of a damaged liver. It’s important to note that by the time these levels are above normal, damage to the liver is already happening. So we don’t want to wait until then to care for and support the health of our liver. 

The good news is that livers regenerate and that our body has an amazing ability to heal. It will need some support from us, but an unhealthy liver, even most diseased livers, with the exception of cirrhosis, can be become healthy and well-functioning again. 

In the next episode, I am going to share ways that you can support your liver health to prevent an unhealthy, sluggish, or diseased liver, as well as ways that you can help your liver to heal if you are already experiencing liver dysfunction or disease. Make sure you stay tuned for that episode! 

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